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2-iodobenzoic acid : ウィキペディア英語版
2-Iodobenzoic acid

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2-Iodobenzoic acid, or ''o''-iodobenzoic acid, is an organic compound with the formula IC6H4COOH. The synthesis of 2-iodobenzoic acid ''via'' the diazotization of anthranilic acid is commonly performed in university organic chemistry labs. One of its most common uses is as a precursor for the preparation of IBX and Dess–Martin periodinane, both used as mild oxidants.
== Synthesis ==
2-Iodobenzoic acid can be synthesized ''via'' a Sandmeyer reaction consisting of the diazotization of anthranilic acid followed by a diazo replacement. First anthranilic acid is treated with nitrous acid in order to convert the amino group into the diazo group. The diazo group is ejected, yielding a carbocation which is then attacked by the highly nucleophilic I anion.
The nitrous acid is usually generated ''in situ'' from sodium nitrite.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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